Asian Journal of Research In Chemistry
  • Year: 2012
  • Volume: 5
  • Issue: 5

Microwave Induced Synthesis and Antimicrobial Activity of Some Sodium 4-[Diphenyl-4, 41-Diylbis (Diazene -2, 1-Diyl) Bis (1-Aminonaphtholene 4-Sulfonate)] Derivatives

  • Author:
  • Nirupma Jadon1,, Sadhana Singh1, Kuldeep Singh Jadon2
  • Total Page Count: 4
  • Page Number: 659 to 662

1Department of Chemistry, SBP Govt. College, Dungarpur (Raj.)

2Department of Plant Pathology, RCA, Udaipur (Raj.) India 313001

*Corresponding Author E-mail: nirupama.jadon@gmail.com

Online published on 7 February, 2013.

Abstract

The title compound were synthesized by the diazotized tetrazotised (bis-diazotised) benzidine (1) coupled with naphthionic acid solution under microwave irradiation (MW)1to get sodium 4 –[diphenyl-4,41diylbis (diazehe-2, 1diyl) bis (1-aminonaphthalene-4-sulfonate)] (2). Which then treated with conc. Sulphuric acid, Benzoyl chloride and NaOH, Sodium bisulphite and NaOH to give derivatives sodium 4-[diphenyl – 4, 41-diylbis (diazene-2, 1 -diyl) bis (6-sulfo-1-amino naphthalene sulfonate)] (2a), Sodium 4-[diphenyl -4, 41-diylibis (diazene-2,1-diyl) bis (N-benzoyl) naphthalene sulfonate] (2b), Sodium 4-[diphenyl -4, 41diylbis (diazene -2,1 -diyl) bis (1-hydroxynaphthalene -4sulfonate)] (2C), under microwave irradiation.

Newly synthesized compounds were confirmed by IR and mass analysis. The synthesized compounds were screened for their antimicrobial activity in vitro.

Keywords

Microwave irradiation, solvent free path, one pot synthesis, some sodium 4-[diphenyl – 4,41diylbis (diazene-2,1 -diyl) bis (1-aminonaphthalene -4-sulfonate)] derivatives, antimicrobial activity