Green Sythesis of Novel Heterocycles Carrying Triazole Derivatives of Dihydropyrimidine.

The novel heterocycles, Ethyl -6-methyl-2-oxo-4-(2-phenyl -1,2,3-triazol-4-yl) -3,4 dihydropyrimidine-5carboxylate (4) have been synthesized from 1,3-dicarbonyl compounds, appropriate aldehyde and urea or thiourea under green method. 6– Methyl – 4 –(2-phenyl -1,2,3-triazol-4-yl) –5-(5-substituted phenyl -1, 3, 4–oxadiazol -2-yl) 3, 4-dihydropyrimidine-2(1H)-one (6 a-g) have been synthesized from comp. (4) using hydrazine hydrate, substituted benzoic acid, phosphorous oxychloride by microwave irradiation reported in literature. Above synthesized heterocycles 6 a-g irradiated under microwave with hydrazine hydrate to get amino triazole derivatives of dihydropyrimidine 7 a-g.

The structures of newly synthesized compounds have been confirmed by IR and ¹H NMR spectra.