1Research Laboratory of Pure and Applied Chemistry, Maharashtra, Mahavidyalaya, Nilanga
2Asst. Prof., Department of Chemistry, Shri Madhavrao Patil Mahavidyalaya, Murum
3Asst. Prof., Department of Chemistry, Shivneri Mahavidyalaya, Shirur Anatpal
4Asst. Prof., Department of Chemistry, Rajarshri Shahu, Mahavidyalaya, Latur
*Corresponding Author E-mail: sushilrswami@gmail.com/amritkund_jk@yahoo.com
Online published on 7 February, 2013.
The novel heterocycles, Ethyl -6-methyl-2-oxo-4-(2-phenyl -1,2,3-triazol-4-yl) -3,4 dihydropyrimidine-5carboxylate (4) have been synthesized from 1,3-dicarbonyl compounds, appropriate aldehyde and urea or thiourea under green method. 6– Methyl – 4 –(2-phenyl -1,2,3-triazol-4-yl) –5-(5-substituted phenyl -1, 3, 4–oxadiazol -2-yl) 3, 4-dihydropyrimidine-2(1H)-one (6 a-g) have been synthesized from comp. (4) using hydrazine hydrate, substituted benzoic acid, phosphorous oxychloride by microwave irradiation reported in literature. Above synthesized heterocycles 6 a-g irradiated under microwave with hydrazine hydrate to get amino triazole derivatives of dihydropyrimidine 7 a-g.
The structures of newly synthesized compounds have been confirmed by IR and 1H NMR spectra.
Dihydropyrimidines, Oxadiazole, Triazole, hydrazine hydrate, Green Method
