Asian Journal of Research In Chemistry
  • Year: 2012
  • Volume: 5
  • Issue: 8

Oxadiazole: A Promising Class with Different Pharmacological Activity

  • Author:
  • Tukaram M. Kalyankar1,, Rajendra B. Kakade2, Praveen B. Harshe1
  • Total Page Count: 8
  • Page Number: 1084 to 1091

1School of Pharmacy, S R T M University, Nanded-431606, India

2University Dept. of Pharmaceutical Sciences, Rashtrasant Tukadoji Maharaj Nagpur University, Campus, Nagpur-440033

*Corresponding Author E-mail: dr.kalyankartm@gmail.com

Online published on 7 February, 2013.

Abstract

Oxadiazoles are the class of five membered heterocyclic ring structures which is the flexible lead structure for new important biological activity. This has the important place to synthesis of class of different pharmacological activities. Among a wide variety of heterocyclic that have been explored for developing pharmaceutically important molecules, oxadiazole have played important role in Medicinal Chemistry. Moreover, oxadiazoles have acquired a special place in heterocyclic field because of their diversified activities such as antimicrobial, antiinflammatory, antitubercular, anticancer, anticonvulsant properties. A brief review of the literature available on the correlation between the chemical structure and the biological activity of 1,3,4-oxadiazoles.

Keywords

1,3,4-oxadiazole, 2,5-disubstituted-1, 3,4-oxadiazole, Pharmacological activity