1School of Pharmacy, S R T M University, Nanded-431606, India
2University Dept. of Pharmaceutical Sciences, Rashtrasant Tukadoji Maharaj Nagpur University, Campus, Nagpur-440033
*Corresponding Author E-mail: dr.kalyankartm@gmail.com
Online published on 7 February, 2013.
Oxadiazoles are the class of five membered heterocyclic ring structures which is the flexible lead structure for new important biological activity. This has the important place to synthesis of class of different pharmacological activities. Among a wide variety of heterocyclic that have been explored for developing pharmaceutically important molecules, oxadiazole have played important role in Medicinal Chemistry. Moreover, oxadiazoles have acquired a special place in heterocyclic field because of their diversified activities such as antimicrobial, antiinflammatory, antitubercular, anticancer, anticonvulsant properties. A brief review of the literature available on the correlation between the chemical structure and the biological activity of 1,3,4-oxadiazoles.
1,3,4-oxadiazole, 2,5-disubstituted-1, 3,4-oxadiazole, Pharmacological activity