Asian Journal of Research In Chemistry
  • Year: 2012
  • Volume: 5
  • Issue: 9

Synthesis and Characterization of Novel Oxadiazole Derivatives of 2-mercaptobenzothiazol– A Green Approach

  • Author:
  • R.M. Sushil, R.V. Rohikar, G.G. Hanumant, S.K. Akuskar, N.V. Amit
  • Total Page Count: 4
  • Page Number: 1172 to 1175

P.G. Research Center, Department of Chemistry, S.M.P. College, Murum -413605, Maharashtra, India

*Corresponding Author E-mail: amitnv55@gmail.com

Online published on 7 February, 2013.

Abstract

Novel 2-Mercaptobenzothiazole derivatives synthesized from 2-Mercaptobenzothiazole reacted with ethyl chloroacetate to get ester derivatives (3) using Green method. These ester converted to hydrazids (4) by reaction with hydrazine hydrate under MWI. 5-substituted 1,3,4-oxadiazole (5a-g) synthesized from hydrazide, substituted benzoic acid and phosphprous oxochloried by Microwave irradiation as reported in literature. The structure of newly synthesized compound was established by physico-chemical and spectral data analysis.

Keywords

2-Mercaptobenzothiazole, hydrazine hydrate, substituted1,3,4-oxadiazole, substituted benzoic acid, Microwave irradiation