A Review on 1,3-Thiazolidin-4-Ones

1,3-Thiazolidin-4-ones are important group of heterocyclic compounds that are used in the field of medicinal chemistry. The utility of 1,3-thiazolidin-4-ones as synthons for various biological compounds has given impetus to these studies. This review aims to review the work reported on the chemistry and biological activities of 1,3-thiazolidin-4-ones during the past few years. Since a decade extensive research work is undergoing on the thiazolidine ring. Researchers have developed number of new compounds related to1,3-thiazolidin-4-ones further they have screened them for various pharmacological activities to get a molecule with good pharmacological activities and with least adverse effects. The thiazolidine is not only synthetically important scaffold but also possesses a wide range of promising biological activities. Some thiazolidine derivatives have better activity than standard drug and could become a new drug for the market in future. This thiazolidine moiety and its derivatives has shown its importance as antimicrobial, anti-bacterial, anti-tubercular, anti-fungal, anti-inflammatory, analgesic, anti-cancer, anti-proliferative, anti-HIV, anti-retroviral,anti-yellowfevervirus,anti-diarrhoeal,anti-arrythmic agent, anti-convulsant, anti-oxidant, antimalarial.