Asian Journal of Research In Chemistry
  • Year: 2013
  • Volume: 6
  • Issue: 10

Synthesis, Characterization and Biological Studies of Novel Imines of Haloaryloxy Moiety

  • Author:
  • Sachin Rohane1,, Jyoti Wagh2, Vikas Rajurkar, Shivkanya Jajoo
  • Total Page Count: 3
  • Page Number: 900 to 902

1Pharmaceutical Chemistry, Arvind Gavali College of Pharmacy, Shivaji University, Satara, India

2Dept. of Pharmaceutical Chemistry, MES College of Pharmacy, Pune University, Pune, India

*Corresponding Author E-mail: sachinrohane29@gmail.com

Online published on 31 October, 2013.

Abstract

Haloaryloxy moiety on refluxing with chloroethyl acetate in the presence of potassium carbonate and acetone yielded ethyl halolaryloxy acetate (1), which were reacted with hydrazine hydrate to produce haloaryloxyacetyl hydrazine (2), which on treatment with aromatic aldehydes yields imines (3A-E). The novel series of compounds were elucidated on the basis of spectral studies and screened for antibacterial and antifungal studies.

Keywords

Azetidinones, imines, hydrazine, haloaryloxy moiety, antibacterial activity, antifungal activity