Department of Chemistry, Adikavi Nannaya University, Rajahmundry-533105, India
*Corresponding Author E-mail: prudhvi115@gmail.com
Online published on 31 October, 2013.
An Iodine catalyzed (3, 5)-thionium-ene-type cyclization for the facile construction of various multisustituted tetrahydrothiopyrans was successfully developed from aldehyde (aromatic and aliphatic) and 6-methylhept-5-en-2thiol, 6-methyl-2-phenyl hept-5-en-2-thiol and 2, 6-dimethylhept-5-en-2-thiol in the presence of iodine under mild and neutral conditions. This method is simple, convenient and cost-effective.
Molecular Iodine, Thionium ene reaction, 6-methylhept-5en-2-thiol, 6-methyl-2-phenyl hept-5-en-2-thiol and 2, 6-dimethylhept-5-en-2-thiol, 3-isopropenyl-6-methyl-2phenyltetrahydrothiopyran
