1Department of Pharmaceutical Sciences, Bhagwant University, Ajmer, Rajashthan, India
2Department of Pharmaceutical Chemistry, R.G. Sapkal College of Pharmacy, Nashik, M.S., India
*Corresponding Author E-mail: rsk_55@rediffmail.com
Online published on 31 January, 2014.
A novel series of some substituted 5-diaryl substituted-1,3,4-oxadiazole derivatives were prepared from benzoic acid hydrazones with the aim to get better antibacterial activity, antifungal activity, antitubercular and anti-inflammatory activity. Chemical structures of synthesized compounds were supported by means of IR, 1H NMR. Title compounds were evaluated for antibacterial activity, antifungal activity, antitubercular and anti-inflammatory activities. QSAR for the tittle compounds had been performed using TSAR 3.3 software and results were found satisfactory. Among the synthesized compounds some compounds found to possess all these activities.
QSAR, antibacterial, antifungal, antitubercular, anti-inflammatory activity
