1Department of Chemistry, JNT University, Anantapuram, Andhra Pradesh, India.
2Department of Chemistry, KL University, Vaddeswaram, Guntur -522502, A.P, India.
3Department of Chemistry, Krishna University, Machilipatnam -521 001, India.
*Corresponding Author E-mail: vbrmandava@yahoo.com
Online published on 6 May, 2013.
A New and alternate simple synthetic strategy of carvedilol, β-adrenergic blocking agent and its analogs, The key step in this approach is synthesis of 3-(9H-carbazol-4-yloxy)-2-hydroxypropyl 4-methylbenzenesulfonate, it is wished to report towards synthesis of Carvedilol this approach is more efficient, improved overall yield, easy process and to avoid the process impurities.
β-Adrenergic Blocking Agents, antihypertensive efficacy drug Suzuki Coupling, Regioselective Tosylation, Cyclisation, Yields
