1, 2, 4-Triazole Derivatives and its pharmacological activities

Triazole, a heterocyclic nucleus has attracted a wide attention of the medicinal chemist in search for the new therapeutic molecules. This review provides a brief summary of 1,2,4-triazole Derivatives and its Pharmacological activities and highlights some examples of 1,2,4-triazole-containing drug substances. Either as single heterocyclic derivatives or in fusion with the other cycles, these heterocycle is emerging as the most explored centre to obtain clinically significant compounds. The major activities exhibited by 1,2,4 derivatives include antibacterial, antifungal, antiviral, antidepressant, antimalarial, hypnotic, anticonvulsant and anti-inflammatory activities.