Asian Journal of Research In Chemistry
  • Year: 2013
  • Volume: 6
  • Issue: 5

Amino-Indane: Fused Heterocycle with Diverse Pharmacological Activity

  • Author:
  • Prafulla M Sabale1,, Meeraben P. Kakadiya1, Jitendra G. Dobariya2
  • Total Page Count: 10
  • Page Number: 438 to 447

1Department of Pharma. Chemistry, Parul Institute of Pharmacy, Limda-391 760, Vadodara, Gujarat, India

2Darshan Pharma Chem, Plot No. A-1/3621, GIDC Estate, Ankeleshwar, Gujarat, India

*Corresponding Author E-mail: prafullasable@yahoo.com

Online published on 21 September, 2013.

Abstract

Amino-indane is an important structural moiety found in numerous pharmaceutically active compounds. Aminoindane has non-heterocyclic fused ring having six member benzene ring and five member cyclopentane ring with amino group. Amino-indane derivatives play a vital role in the field of medicinal chemistry. This has the important place to synthesis of class of different pharmacological activities. Amino-indane moiety is an important pharmacophore and exhibits outstanding biological activities. A number indane derivatives have acquired a special place in heterocyclic field because of their diversified activities such as antimicrobial, antipyretic, analgesic, anticonvulsant, CNS Depressant anti-inflammatory, anticancer activity. This review emphasized the recent researches in amino-indanes in various diseases and disorders.

Keywords

Indane, Amino-indane, Anti-inflammatory, Pharmacological activity