Department of Chemistry, Veer Narmad South Gujarat University, Surat -395 007
*Corresponding Author E-mail: a.mehta43@yahoo.com
Online published on 21 September, 2013.
Title compounds of 1,3,4-oxadiazoles derivatives by the ring closure reaction of m-fluorobenzoic acid hydrazide with an aromatic acid and alumina in presence of POCl3 under microwave irradiation. All the newly synthesized compounds were screened for their antibacterial activity against Gram-positive bacteria namely staphylococcus aureus, Bacillus subtilis and Gram-negative bacteria namely, Escherichia coli and Pseudomonas aeruginosa. All the synthesized compounds were also tested for their antifungal activity against fungi namely, Candida albicans.
2,5-disubstituted 1,3,4-oxadiazoles, ring closure reaction, antibacterial activity, antifungal activity
