A Current Study on Benzimidazole Derivatives

Benzimidazoles are regarded as a promising class of bioactive heterocyclic compounds that exhibit a wide range of biological activities. Their nucleus is a constituent of vitamin B12 and is present in numerous compounds possessing antioxidant, antiparasitic, anthelmintic, antiproliferative, anti-HIV, anti-allergy, anti-inflammatory, antihypertensive, antineoplastic and antiulcer activity. The present review article is concerned about the heterocyclic chemistry of benzimidazole. Basically it gives emphasis on potential biological activities of benzimidazole derivatives. Benzimidazole is an important lead compound, on modification of the nucleus owing to gives inherent properties and therapeutic action. The present review focuses on the biological activities of the benzimidazoles derivatives reported from 2000 to 2012.