1Research Scholar, Ajmer and Department of Pharmaceutical Chemistry, Bhagwant University, Maratha Mandal's College of Pharmacy, Belgaum-590 016
2Department of Pharmaceutical Chemistry, KLE University's, College of Pharmacy, Rajajinagar, Bangalore-40
*Corresponding Author E-mail: pc_mahe@yahoo.co.in
Online published on 21 September, 2013.
4-substituted acetanilide on treatment with substituted benzaldehyde affords the corresponding chalcones (C13-C24). Further treatment of chalcones with phenylhydrazine undergone cyclocondensation and gave a new series of novel 3, 5-Diaryl-1-aryl-2-pyrazoline (P13-P24). All synthesized compounds were screened for their antibacterial and antifungal activity at 75μg concentration and anti-inflammatory activity at 200mg/kg body weight. Some of the compounds have shown excellent activity.
Pyrazoline, Antibacterial, Antifungal, Anti-tubercular activity
