Asian Journal of Research In Chemistry
  • Year: 2013
  • Volume: 6
  • Issue: 7

Synthesis, Characterization and Antimicrobial Activity of Novel Chalcones from 1-[4-(1H-imidazol-1-yl) Phenyl] Ethanone

  • Author:
  • Gondu Eswara Rao1,, S.A. Rahaman2, A. Prameela Rani3, Ch. M.M. Prasada Rao4
  • Total Page Count: 3
  • Page Number: 687 to 689

1Assistant Professor, NRI College of Pharmacy, Pothavarapadu Village, Agirapalli (M), A.P.

2Professor, Nirmala College of Pharmacy, Atmakur Village, Mangalagiri Mandal, Guntur Dt, A.P -522 503

3Principal & Professor, ANU College of Pharmaceutical Science, Nagarjuna Nagar, Acharya Nagarjuna University, Guntur-530 003, (A.P), India

4Assistant Professor, QIS College of Pharmacy, Vengamukkala Palem, Ongole, A.P-523272

*Corresponding Author E-mail: eswar_gondu@yahoo.com

Online published on 21 September, 2013.

Abstract

Chalcones were synthesized by condensing 1-[4-(1H-imidazol-1-yl) phenyl] ethanone with aromatic aldehydes derivatives in dilute ethanolic sodium hydroxide solution at room temperature according to Claisen-Schmidt condensation. All these compounds were characterized by means of their IR, 1H NMR spectroscopic data and microanalyses. The antimicrobial activity of these compounds was evaluated by the cup plate method.

Keywords

Chalcones, Synthesis, Antimicrobial activity