Synthesis and Characterization of Novel Bio-Elastomers for Tissue Engineering

Biodegradable elastomers have recently found widespread application in many areas of biomedical engineering such as tissue engineering, therapeutic delivery and bioimaging. Recent developments led to development of elastomers involving citric acid based polyesters are being explored that are endogenous to the human metabolism. In terms of mechanical stability, crystallinity, hydrophobicity and biocompatibility, polyesters synthesised from these monomers can display a wide range of applications. In this investigation, a series of novel bio-elastomers based on citric acid were synthesised by catalyst free polycondensation reaction. These polymers were characterised by solubility, IR, 1H NMR spectral analysis, thermal and mechanical studies. The physicochemical properties of the synthesised polymers are controlled by the variation of monomers in polycondensation reaction forms a pivotal role in the synthesis.