Centre for Drug Research, Universiti Sains Malaysia, Penang-11800, Malaysia
*Corresponding Author E-mail: gohteikbeng@yahoo.com
Online published on 31 October, 2013.
An efficient and simple one pot method for the conversion of mitragynine picrate to 9-hydroxycorynantheidine picrate was investigated for yields, selectivity and conversion in comparisons with the CYP2D6 enzyme. By applying this particular version of procedure, preparation of various ester derivatives based on position carbon 9 will be investigated.
Mitragynine picrate, 9-hydroxycorynantheidine, yields, conversion, selectivity