Mononuclear Complexes Constructed by First Series Transition Metals and 2,6 Substituted Pyridine-Glutarimide Ligand: Structures, Electrochemical and Biological Properties

Hexa-aza-macrocyles containing glutarimide efficiently coordinate as hexa-dentate ligand to give complexes of Cu(II) possessing tetragonal structure and Mn(II), Co(II) and Ni(II) metal ions that are essentially octahedral. The chelation of the complexes have been elucidated in the light of analytical, IR, UV–Vis, mass, ESR spectral data and magnetic studies. The measured molar conductance values indicate that the complexes are electrolytic in nature. The redox behavior of one of the synthesized metal complexes were investigated by cyclic voltammetry. The Schiff's base and its metal complexes have been screened for their in vitro antibacterial activities.

A new hexadentate nitrogen donor Schiff's base ligand has been synthesized by the condensation of 2,6-diamino pyridine with glutarimide. The metal(II) complexes are prepared using the Schiff's base. All the complexes have been characterized based on the spectral and analytical data. Antimicrobial activities have been carried out for Schiff's base and its complexes. Redox behaviour of Ni(II) complex has been investigated.