Asian Journal of Research in Chemistry
  • Year: 2014
  • Volume: 7
  • Issue: 11

Synthesis and Antifungal Screening of Novel Pyrimidine-carbonitriles

  • Author:
  • Chetan M. Bhalgat, B. Ramesh
  • Total Page Count: 4
  • Page Number: 905 to 908

Department of Pharmaceutical Chemistry, Sri Adichunchanagiri College of Pharmacy, B.G. Nagara-571448, Nagamangala (Tq.), Mandya (Dist.), Karnataka, India

*Corresponding Author E-mail: chetanbhalgat2004@gmail.com

**rambha_vin@yahoo.com

Online published on 10 February, 2015.

Abstract

In the present study, a series of novel pyrimidines were synthesized. Structures of the synthesized compounds were established by IR, 1H NMR and mass spectral data. All the newly synthesized compounds were screened for their in vitro antifungal activities. Among the compounds tested, few were found to be most effective antifungal agents. The results revealed that the synthesized compounds may be potential lead for future drug discovery.

Keywords

Pyrimidine, Synthesis, Spectral analysis, Antifungal activity