A new series of 2-oxo-azetidine derivatives of isoniazid have been synthesized and evaluated for their Anti-bacterial, Antifungal and Anti-tubercular activity. Synthesized compounds show significant activity against bacterial, fungal and mycobacterium strains. Their structures were established on the basis of elemental analysis, IR, 1H NMR and Mass Spectral data.
INZ, Isoniazid, azetidine, antimycobacterial, TB