Asian Journal of Research in Chemistry

  • Year: 2014
  • Volume: 7
  • Issue: 11

Synthesis and Antimicrobial Screening of Some 4-Substituted-3-Chloro-2-Oxo-Azetidine Derivatives

  • Author:
  • Rakesh Patel1,, Anil Bhandari2
  • Total Page Count: 4
  • DOI:
  • Page Number: 950 to 953

1Charak Institute of Pharmacy, Mandleshwar (Khargone) M P

2Department of Pharmacy, Jodhpur National University, Jodhpur (Raj)

Abstract

A new series of 2-oxo-azetidine derivatives of isoniazid have been synthesized and evaluated for their Anti-bacterial, Antifungal and Anti-tubercular activity. Synthesized compounds show significant activity against bacterial, fungal and mycobacterium strains. Their structures were established on the basis of elemental analysis, IR, 1H NMR and Mass Spectral data.

Keywords

INZ, Isoniazid, azetidine, antimycobacterial, TB