Studies on Synthesis, Characterization and Biological Activity of Mixed Ligand Coordinating Co (II) Complexes

The mixed ligand complexes of Co(II) with amino acids and heterocyclic amines have been synthesized and characterized on the basis of metal estimation, conductivity and magnetic measurements, infrared spectra and electronic spectra studies. The complexes were of [M(X)L] where M = Co(II) and X= deprotonated amino acids as a primary ligand, such as glycine and cysteine; L= heterocyclic amines as a secondary ligand, such as quinoline, isoquinoline pyridine, 1,10-phenanthroline, 8-hydroxyquinoline, 2-picoline, 4-picoline. Antibacterial activity of the complexes has been examined against six (gram positive and gram negative) pathogenic bacteria by disc diffusion method and compared with that of standard antibiotic (Kanamycin). The complexes have been found to have moderate to strong antibacterial activity against the tested bacteria.