Medicinal Chemistry Laboratory Research Center, C. K. M. Arts and Science College, Kakatiya University, Warangal-506 006, Andhra Pradesh, India
*Corresponding Author E-mail: mrgangula@yahoo.com
Online published on 27 March, 2014.
In this article we focused on the synthesis and characterization of [2-(2,4-dinitrophenylsulfanyl)benzimidazol-1-yl]acetic acid (substituted-benzylidene) hydrazides (7a-g) and 5-[2-(2,4-dinitrophenylsulfanyl)benzimidazol-1-ylmethyl]-[1,3,4]-oxadiazole-2-thiol (8) derived from 2-{2-[(2,4-dinitrophenyl)sulphanyl]-1H-benzimidazol-1-yl}ethanohydrazide (6). Compound 6 was achieved from 1H-benzimidazole-2-yl-(2,4-dinitrophenyl) sulphide (4) with ethyl chloroacetate followed by treatment with hydrazine hydrate. The newly synthesized compounds were characterized by elemental analysis, IR, 1H NMR and Mass spectral data.
1H-Benzimidazole-2-thiol, acetic acid ethyl ester, ethanohydrazide, oxadiazole-2-thiol
