Asian Journal of Research In Chemistry
  • Year: 2014
  • Volume: 7
  • Issue: 2

Synthesis and anti-tubercular activity of some n-substituted and 2-substituted benzimidazole derivatives

  • Author:
  • Pankaj S. Kore, Sachin G. Lokpaure, Somkant V. Jawarkar, S K. Mohite, C S. Magdum
  • Total Page Count: 4
  • Page Number: 137 to 140

Department of Pharmaceutical chemistry, KES's Rajarambapu College of Pharmacy, Kasegaon, Maharashtra (India)

*Corresponding Author E-mail: sachinlokapure@yahoo.in

Online published on 27 March, 2014.

Abstract

The two series of N-substituted and 2-substituted benzimidazole derivatives, viz. 1-benzyl-2-substituted benzimidazole and 1-(p-chloro phenyl)-2-substituted benzimidazole have been synthesized and tested for their anti-tubercular activities. These compounds have been screened for their anticonvulsant activity, the compound 1A, 1G was found to possess significant anti tubercular activity as compared with Rifampicin.

Keywords

Benzimidazole derivatives anti-bacterial, anticonvulsant, anti-tubercular activities