Asian Journal of Research In Chemistry
  • Year: 2014
  • Volume: 7
  • Issue: 3

Investigation of Phytoconstituents, from Momordica charantia Linn Roots and Screening them, for Anti-Hyperglycemic Activity

  • Author:
  • F. Nikhat1,3,, D. Satyanarayana2, C.S. Shastri3, A. Moid2, A. Thouheed2
  • Total Page Count: 6
  • Page Number: 256 to 261

1Department of Pharmaceutical chemistry, NGSMIPS, Deralakatte, Mangalore

2Department of Pharmaceutical chemistry, VIP Sciences, Rajahmundry, AP

3Department of Pharmacy, AIKTC School of Pharmacy, New Panvel, Mumbai

*Corresponding Author E-mail: nik.nida13ada25@gmail.com

Online published on 19 June, 2014.

Abstract

Momordica charantia is a well known plant in Asia including India which posses wide range of pharmacological activities. The plant have been used as drug in India as folk remedy in the form of decoctions and infusions to treat the deficiency disease such as anti-hyperglycemic activity.

The entitled work is entirely depends on the investigation of chemical compounds which are responsible for anti-hyperglycemic activity. The research avenue made over here get succeeded by endorse new moiety from the roots of the plant belonging to the group of alkaloids, amino acids and glycosides this are coded as McReX-1 McReX-2, McReX-3, McReX-4, McReX-5, McReX-6, the present article will gives only chemical names and spectral interpretation, among above all moiety McReX-5 have been shown a resemble anti-hyperglycemic activity when compared with glibencalimide in STZ induced diabetic rat model

Keywords

Momordica charantia, Linn, Cucurbitaceae, antidiabetic, alkaloids, glibencalamide