1Faculty of Chemistry, S.S.B.N. Degree College, Anantapur
2Faculty of Chemistry, Sri Chaitanya Jr. College, Anantapur
3Department of Chemistry, S.K. University, Anantapur
Online published on 19 June, 2014.
Analytical determination of Taxim-of and cobalt(II) in pharmaceutical formulation is carried and based on a colour reaction between the two. cobalt(II) forms pinck coloured complex with Taxim-of in a buffer of pH – 6. This method can be conveniently used for the determination of cobalt (II) and Taxim-of, in the ranges of cobalt (II) 0.73 – 5.15 μg/ml and Taxim-of in the range of 1 to 6 mg/ml. The method is successfully applied for the determination of Taxim of and cobalt(II) in pharmaceutical formulation. Effect of various parameters, pH, metal ion concentration, drug concentration of solutions is studied. The optimum condition are established for the determination of cobalt(II) and the drug.
Spectrophotometric method1, Taxim-of and cobalt(II) system
