Asian Journal of Research In Chemistry
  • Year: 2014
  • Volume: 7
  • Issue: 3

Novel Synthesis of 2-Iminothiazoline Derivatives were Achieved by the Reaction Thiourea derivatives

  • Author:
  • B. Satyanarayana, P. Muralikrishna, B. Sriramudu, D. Ramachandran
  • Total Page Count: 4
  • Page Number: 335 to 338

Department of Chemistry, Acharya Nagrjuna University, Guntur-522510, (A.P), India

*Corresponding Author E-mail: dittakavirc@gmail.com, boyinasatyam@gmail.com

Online published on 19 June, 2014.

Abstract

The syntheses of 2-iminothiazoline derivatives were achieved by the reaction thiourea derivatives with various substituted α-bromoketone in the presence of suitable basediisopropyl amine. Here also we adopted the similar reaction procedure for the synthesis of 4-amino-2-iminothiazoline derivatives from the reaction of various arylthiourea derivatives with a variety of bromobenzyl cyanides. In order to improve the yield of the desired product, we have screened several reaction conditions.

Keywords

2-iminothiazoline, Synthesis, 4-amino-2-iminothiazoline, diisopropyl amine