Cyanoacrylate: A Bio Adhesive for Suture less Surgery: A Review

Bioadhesion refers to the phenomenon where natural and synthetic materials adhere to biological surfaces. An understanding of the fundamental mechanisms that govern bioadhesion is of great interest for various researchers who aim to develop new biomaterials, therapies and technological applications such as biosensors. This review paper will first describe examples of Cyanoacrylates the manifestation of bioadhesion along with the underlying mechanisms. This will be followed by a discussion of Cyanoacrylates for the optimization of bioadhesion. An ideal bio adhesive should offer combination of high bond strength, ability to cure in a moist environment, and biological compatibility/minimal toxicity; though not seen in earlier Cyanoacrylates, has been observed in long chain Cyanoacrylates like Isoamyl -2 Cyanoacrylates