Synthesis, Characterization and Antimicrobial Screening of Some Novel Chromonyl Chalcones

Synthesis of some novel 6-acetyl-2-aryl/furyl chromones [4(a-b)] by Friedal-Craft's acylation of 2-aryl/furyl chromones [3(a-b)] and 1-(2’-aryl/furyl chromon-6’-yl)-3-aryl or heteroarylprop-2-en-1-ones [5(a-f)] by Claisen-Schmidt condensation is being reported in this publication. The synthesized compounds have been characterized by elemental analysis, FT-IR and PMR spectral data. The synthesized compounds have been evaluated for their antibacterial and antifungal activities. Most of the compounds have been found moderately active when compared with the reference standard drugs.