Department of Chemistry, Pratishthan Mahavidyalaya Paithan, Dist. Aurangabad (M.S.) 431107, India
*Corresponding Author E-mail: sg_sonkamble@yahoo.co.in
Online published on 22 October, 2014.
The potentiometer studies have been carried out on metal complexes of Fe(III), Cd(II), Co(II), Ni(II), Zn(II) with drug diazepam [7-chloro -1-methyl -5-phenyl -3H-1,4-benzodiazepine -2-one]. The proton ligand, metal ligand and the formation constants have been determined by adopting Irving-Rossotti Method and by computer programming (SCOSS) an ionic strength 0.1 M ethanol – water medium. pK1 and pk2 valve were determined by half –integral method. Thermodynamic parameter also evaluated at 0.1 M ionic strength.
Potentiometer, diazepam, Thermodynamic parameter, The proton ligand, metal ligand formation constants
