Asian Journal of Research in Chemistry

  • Year: 2015
  • Volume: 8
  • Issue: 1

Cadmium Chloride (CdCl2): An Efficient Catalyst for the Synthesis of Substituted Thiazoles

Department of Chemistry, University College for Science, Osmania University, Hyderabad-500007, India

Abstract

A variety of α-bromoketones undergoes smooth condensation with thiourea compounds to afford the Corresponding substituted thiazole derivatives in very good to excellent yields. The condensation reactions were carried out in presence of cadmium chloride in acetonitrile at room temperature.

Keywords

Acetonitrile, Bromoketone, CdCl2, thiourea, urea, thiazole