1Department of Pharmaceutical Chemistry, M.M.U College of Pharmacy, K.K. Doddi, Ramanagara-562159, Karnataka
2Department of Chemistry, Jawaharlal Nehru Technological University Anantapur, Ananthapuramu-515002, Andhra Pradesh
Benzopyrone derivatives are associated with different pharmacological activities like analgesic, anti-inflammatory, anticancer, antihepatotoxic, antibacterial, antiviral etc. Considering the potential of this particular lead molecule, different derivatives of benzopyrone condensed with amines were synthesized and evaluated for their analgesic activity. The structures of the synthesized compounds were confirmed by their analytical as well as spectral data. Some of the compounds synthesized i.e. 4a, 4c, 4e and 4g showed significant analgesic activity.
Analgesic activity, Amines, Tail flick method
