Comparative evaluation of marketed formulations of Metformin HCl. available in India

Metformin HCl is an oral Anti-diabetic drug belongs to the class of biguanide derivatives commonly used to treat type 2 diabetes mellitus. The study was conducted to assess the comparative in-vitro quality control parameters through the evaluation of mechanical strength, dissolution study in buffer solution, content and weight uniformity between the commercially available conventional and modified (sustained release) tablets of different brand of Metformin in India. It can be concluded that standard quality control parameters always should be maintained not only for Metformin but also for all kinds of medicine for getting better drug products.