1Reserch Lab of Pure and Applied Chemistry, Maharashtra Mahavidhyalaya, Nilanga, Dist: Latur
2Department of Chemistry, K M C College, Khopoli, Dist Raigad
3Department of Chemistry, S. M. P. College, Murum, Omerga, Dist: Osmanabad
4Department of Chemistry, Shivneri Mahavidhyalaya, Shirur Anantpal, Dist Latur
5Department of Chemistry, Rajshri Shahu Mahavidhyalaya, Latur
*Corresponding Author E-mail: amritkund_jk@rediffmail.com
Online published on 9 March, 2017.
Numerous imidazole derivatives are reported as pharmacological agents like azomycin, clotrimazole, Miconazole, ergothionine, clonidine and moxonidine. One of the most important applications of imidazoles derivatives are treatment for denture and cancer therapy. Imidazoles are in general, well known to possess, anti-cancer activity. These compounds are 5 membered planar ring, soluble in water and other polar solvents. Radziszewski and Jaapproposed the first synthesis of the imidazole corein 1882, starting from 1,2-dicarbonyl compounds, aldehydes and ammonia to obtain 2,4,5-triphenylimidazole [1, 2].
Imidazole, Zinc Sulphate, trisubstitution etc
