1Department of Pharmacy, Pacific University, Udaipur, Rajasthan-313003
2Department of Quality Assurance Techniques, KCT's R. G. Sapkal College of Pharmacy, Anjaneri, Nashik
A simple, accurate, precise, and sensitive a highly selective ultra violet spectrophotometric method has been developed for the estimation of drug in bulk and dosage form. It shows maximum absorbance at 238nm. The Beer-Lambert's law was obeyed in the concentration range of 5–35μg/ml. The linear regression analysis data for calibration plots showed good linear relationship and obtain correlation factor for Simvastatin. The percentage recovery was found to be within range. Thus method was successfully applied for routine analysis of Simvastatin in bulk drug and dosage form.
Simvastatin, UV-method, Spectrometric method, Determination