Synthesis and evaluation of analogues of indole

It was mentioned earlier in this chapter that a large number of compounds containing indole nucleus have been patented, as chemotherapeutic agents, antimicrobial, cytotoxic, anti-inflammatory, antitumor, anti-convulsant, antitubercular and anti-HIV. A wide range of indole derivatives were investigated using different conditions. In the present work we synthesized various indole derivatives which are given below in scheme-1.1 and summarized in after the scheme.