1Department of Pharmacognosy, RKDF College of Pharmacy, Bhopal (M.P.), India
2Department of Pharmacognosy, Lakshminarain College of Pharmacy, Bhopal (M.P.), India
*Corresponding Author E-mail: yogesh_aot@rediffmail.com
Online published on 5 June, 2014.
The Present Study was planned to assess the acute toxicity of Coccinia indica roots. Rats were orally administrated single dose of 100, 500 and 1000mg/kg of aqueous extract of Coccinia indica. Mortality, signs of toxicity, body weight, food consumption and gross findings were observed for 07 days post treatment of Coccinia indica extract. In addition, no significant differences were noticed in the body and organ weights between the control and treated groups. These results state that aqueous extract of Coccinia indica is toxicologically safe by oral administration.
Acute toxicity, Coccinia Indica, Roots
