Asian Journal of Research in Pharmaceutical Science

Antibiotics are most widely used therapeutics among drugs, which exerts their therapeutic effects by inhibiting the growth of bacteria. For decades various classes of antibiotics have not only been used in medical sector but are used in various other sectors such as agriculture and animal husbandry. Due to overuse of antibiotics, the process of antibiotic resistance is increases. Antibiotic resistance is one of the important factors involved in public health authorities at global level. The main aim of this review is to explain the phenomenon of antibiotic resistance, history and biology of antibiotic resistance involving various mechanisms of resistance. It also explains about antibiotics their history, mode of action and classification of antibiotics and how to reduce the spread of antibiotic resistance.