1PRES Institute of Pharmacy, Loni, Tal - Rahata, Dist - Ahmednagar (M S), India
2SCS College of Pharmacy, Harpanhalli, Dhavangiri, District (K S), India
*Corresponding Author E-mail: dattatraya_thorat@rediffmail.com
Ten different 2, 7-disubstituted [1, 3, 4]-thiadiazolo [2, 3-b] quinazolin-5(4H)-ones were synthesized by action of 3-amino-2-mercaptoquinazolin-4(3H)-ones with various aliphatic and aromatic acid chloride in the presence of phosphorousoxy chloride. The newly synthesized compounds have been characterized by their analytical and spectral (IR, 1HNMR and Mass) properties. Further, they have been screened for their anti-inflammatory (in vitro and in vivo) by standard method.
Quinazolinones, Thiadiazoloquinazolinone, Anti-inflammatory activity (In-vitro), Antiinflammatory activity (In-vivo), Bovine albumin
