Asian Journal of Research in Pharmaceutical Sciences
  • Year: 2024
  • Volume: 14
  • Issue: 3

Exploring the advancements and applications of oral thin film technology

  • Author:
  • Taufik Mulla1,*, Tahoora Ansari2, Namira Saiyed3, Aashka Desai4, Bhavin Pandya4
  • Total Page Count: 10
  • Published Online: Apr 22, 2025
  • Page Number: 317 to 326

1Department of Pharmaceutics, Institute of Pharmaceutical Sciences, Parul University, Vadodara, Gujarat, India

2Allana College of Pharmacy, A Constituent College of Dr. P.A. Inamdar University, Pune, Maharashtra, India

3Faculty of Pharmacy, The Maharaja Sayajirao University, Baroda, Gujarat, India

4Krishna School of Pharmacy and Research, Affiliated with Drs. Kiran and Pallavi Patel Global University, Varnama, Vadodara, Gujarat, India

*Corresponding Author E-mail: mullataufik@gmail.com

Online published on 22 April, 2025.

Abstract

This comprehensive review delves into the recent advancements and diverse applications of oral thin film (OTF) technology in the field of pharmaceuticals. The aim is to provide a thorough exploration of the evolution of OTFs, their unique characteristics, and their expanding role in drug delivery systems. A systematic analysis of the literature was conducted to gather information on the formulation techniques, properties, and challenges associated with OTFs. Additionally, recent developments, innovations, and future trends in OTF technology were examined to understand the dynamic landscape of this drug delivery system. The review highlights the key properties of OTFs, including rapid disintegration, enhanced bioavailability, and patient-centric advantages. Various manufacturing techniques, such as solvent casting, hot melt extrusion, and 3D printing, were explored for their impact on OTF formulation. Challenges, including stability issues and taste masking complexities, were identified. Recent innovations, such as nanotechnology integration, personalized medicine applications, and the use of digital health platforms, showcase the ongoing efforts to overcome these challenges. Oral thin film technology stands at the forefront of pharmaceutical innovation, offering a patient-friendly and adaptable drug delivery system. As evidenced by recent developments, the integration of advanced technologies, personalized medicine approaches, and sustainable practices positions OTFs as a transformative force in the future of drug delivery. The exploration of these advancements and applications contributes to a deeper understanding of the potential impact of OTF technology on healthcare.

Keywords

OTF (Oral Thin Film), Novel Drug Delivery System, Nanotechnology