1Assistant Professor,
2Research Scholar,
*Corresponding Author E-mail: payalvaja55@gmail.com
Inflammatory Bowel Disease (IBD), encompassing Crohn’s Disease (CD) and Ulcerative Colitis (UC), is a persistent and relapsing inflammatory disorder of the gastrointestinal (GI) tract. Though the exact cause remains unidentified, various factors such as genetic predisposition, environmental influences, immune dysfunction, and alterations in gut microbiota are believed to play key roles in disease onset. CD may affect any portion of the GI tract, especially the ileum and colon, with patchy and deep tissue inflammation. In contrast, UC is limited to the colon and involves continuous inflammation of the mucosal lining. Both conditions are characterized by symptoms like abdominal pain, diarrhoea, fatigue, and weight loss, and may lead to serious complications including strictures, fistulas, and an elevated risk of colorectal cancer. Conventional treatments include anti-inflammatory drugs, immunosuppressants, lifestyle modifications, and surgery. However, limitations such as side effects and inconsistent therapeutic outcomes have prompted interest in alternative strategies. Indian medicinal plants have emerged as promising options due to their anti-inflammatory, antioxidant, immunomodulatory, and gut-healing properties. This review explores the therapeutic potential of ten key plants, including Withaniasomnifera, Curcuma longa, Nigella sativa, and Boswellia serrata. Their bioactive compounds target inflammatory pathways and support mucosal protection, offering a natural and complementary approach to IBD management. Integrating traditional herbal remedies with modern treatment could enhance patient outcomes and promote holistic care.
Inflammatory Bowel Disease (IBD), Indian medicinal plants, Crohn’s Disease, Ulcerative Colitis, Anti-inflammatory phytochemicals, Immunomodulatory herbs