Asian Journal of Research in Pharmaceutical Science
  • Year: 2012
  • Volume: 2
  • Issue: 4

Antihepatotoxicity of Hygrophila auriculata on CCl4 Induced Hepatotoxicity in Rats

  • Author:
  • T.S. Dhanaraj, R. Gowthami, S. Rajlakshmi, K. Murugaiah
  • Total Page Count: 3
  • Page Number: 140 to 142

PG & Research Department of Biochemistry, Enathi Rajappaa College, Enathi, Pattukkottai, Thanjavur Dt., Tamil Nadu, India -614 615

*Corresponding Author E-mail: ramanisethu@yahoo.com

Online published on 5 June, 2014.

Abstract

The objective of this study was to investigate the hepatoprotective activity of crude aqueous extract of leaves of Hygrophila auriculata against CCl4 induced hepatotoxicity. The leaves was dried in shade, they were powdered and Extracted with aqueous. The biochemical markers of hepatic damage like tested as MDA, GSH, Protein, Bilirubin, SGOT, ALP and SGPT recorded a significant alteration in CCl4 treated rats. However treatment with Hygrophila auriculata restored the level to near normal was observed. The potential hepatoprotective activity of Hygrophila auriculata is due to the presence of phytochemical constitution such as flavonoids and polyphenolic compounds present in plant.

Keywords

Hepatoprotective, CCl4 – Induced, Hygrophila auriculata