The present study was conducted to find out the detoxification ability of commonly available adsorbents like sodium bentonite (NaB) and activated charcoal (AC) against aflatoxin B1 (AFB1) in post-ruminant goat kids based on exerted effect on blood parameters. Twentyfour male goats (11.91 ± 0.36 kg) were randomly divided into six treatment groups on body weight basis after adapting them on a basal ration consisting of concentrate mixture (maize grain, 25%; barley grain, 27%; groundnut cake (expeller), 10%; mustard cake 10%; wheat bran, 25%; mineral mixture, 2%; salt, 1%) and green maize fodder. The treatment groups were T1 (Basal ration), T4 (T1 + AFB1 @ 300 ppb), T2 (concentrate mixture supplemented with NaB @ 2 kg per 100 Kg), T5 (T2 + AFB1 @ 300 ppb), T3 (concentrate mixture supplemented with activated charcoal (AC) @ 2 kg per 100 Kg), T6 (T3 + AFB1 @ 300 ppb). The serum protein, albumin and globulin values (g/100ml) were found to be similar (P>0.05) between T1 and T4; T2 and T5; T3 and T6 indicating the dose level of 300 ppb did not cause severe liver damage. Serum urea concentration was significantly (P < 0.05) declined at 2 months after the experiment in AFB1 fed kids (T4) compared to its control. NaB has got protective effect on serum urea concentration at the end of the experiment whereas AC has got protective effect throughout the experiment. Non-significant (P>0.05) elevation of serum GOT (units/ml) at one month after the experiment in case of T4 (81.73 ± 8.81) and T5 (80.31 ± 12.81) was observed compared to their respective controls. However, the elevation was not conspicuous in T6 (64.26 ± 3.81) at one month after the experiment indicating the detoxification ability of AC. Alkaline phosphates values have been significantly lowered (P < 0.05) in T6 from the initial values indicating detoxification ability of AC against AFB1 compared to NaB supplemented group. It may be concluded from the results that AC had exerted complete detoxification effect whereas NaB had exerted partial effect based on studied blood parameters.
Activated charcoal, Aflatoxin B1, Bentonite, Goats
