1School of Life Science, Pt. Ravishankar Shukla University, Raipur-492 010, Chhatisgarh, India.
Department of Zoology, Govt. Holkar (Model, Autonomous) Science College, Indore-452 001, Madhya Pradesh, India.
*Corresponding Author: S. Gaherwal, Department of Zoology, Govt. Holkar (Model, Autonomous) Science College, Indore-452 001, Madhya Pradesh, India, Email: psgaherwal@yahoo.com
Online Published on 03 September, 2022.
In new age, Arsenic is a major environmental pollutant and exposure occurs through agricultural, environmental, medicinal and occupational sources. The toxicity of sodium arsenate has been shown in catfish, Clarias batrachus and the histology report suggested that the sodium arsenate may adversely effect on the catfish, Clarias batrachus.
The histological analysis carried out during the period of 2018–19 for sodium arsenate with Clarias batrachus as test animal for 96 hour as per ideal method and determine the lethal concentration (LC50). The liver and kidney tissues were collected from the fishes exposed to sodium arsenate and standard histology procedure were followed to investigate the histological alterations.
Exposure of sodium arsenate causes severe histological changes in liver like nucleus blabbing, infiltration, necrosis of hepatocytes, disruption of normal architecture, shrunkeri hepatocytes, lytic hepatocytes etc. In kidney sodium arsenate exposure causes hemorrhage, inflammation and tubular atrophy in renal tubules, disruption of tubular linings, dense chronic inflammation, hemorrhage and vacoulation in Bowman's capsule etc. The present investigation suggests that the inorganic forms of arsenic showing the highest toxicity level.
Clarias batrachus, Heavy metals, Histology, Kidney, Liver, Sodium arsenate
