1Department of Virology, Faculty of Veterinary Medicine, Burdur Mehmet Akif Ersoy University, Burdur, Turkey
2Department of Pathology, Faculty of Veterinary Medicine, Burdur Mehmet Akif Ersoy University, Burdur, Turkey
*Corresponding Author: Mehmet Kale, Department of Virology, Faculty of Veterinary Medicine, Burdur Mehmet Akif Ersoy University, Burdur, Turkey, Email: drmkalex@yahoo.com
Online Published on 04 December, 2023.
The canine oral papillomavirus (CoPV) is the cause of oral papillomatosis in all dogs. The purpose of this study is to compare two treatment methods after virological and pathological diagnosis of oral papillomas.
Blood samples were collected from 50 owned and stray dogs of various breeds. The presence of CoPV antigen (Ag) in the blood samples investigated. Tissue samples from the papilloma mass were collected for auto vaccination and histopathological examination. CoPV (Ag) was found in the blood of dogs with papilloma lesions who were randomly divided and treated into two groups. While group 1 receives autologous vaccines and immune-supportive Zylexis™, Group 2 receives PAPILEND™® cream, immune-boosting Zylexis™ and premix powder (vitamin E, zinc, selenium, copper).
The dogs have an average age of 31.9+7.4 months. CoPV (Ag) was detected in half of all dogs with papilloma lesions. The histopathological examination typically revealed an increased epidermal layer. In the treatment of group 1, the mean remission period was 21-30 days. This period was determined to be 15-30 days in 15 animals from the second treatment group. Lesions were successfully treated in all dogs with CoPV (Ag) in both groups. The combination of PAPILEND™® cream, immune-supportive Zylexis™ and premix powder was found to shorten the disease remission period caused by CoPV oral lesions.
Canine oral papillomavirus, Dog, PAPILEND™®, Treatment
