Agricultural Science Digest
SCOPUS
  • Year: 2024
  • Volume: 44
  • Issue: 4

Evaluation of Wound Healing Activity of Teucrium polium on Excisional Wounds in Wistar Rats

  • Author:
  • Kalbaza Ahmed Yassine1,*, Hemida Houari2, Rezgui Houssam1, Hamouta Younes1, Benchohra Mokhtar2, Amara Karim2
  • Total Page Count: 6
  • Page Number: 745 to 750

1Institute of Veterinary and Agronomic Sciences, Batna-1 University, Batna, Algeria

2Institute of Veterinary Sciences, University of Tiaret, Tiaret, Algeria

*Corresponding Author: Kalbaza Ahmed Yassine, Institute of Veterinary and Agronomic Sciences, Batna-1 University, Batna, Algeria, Email: yassine.kalbaza@univ-batna.dz

Online Published on 01 October, 2024.

Abstract

Teucrium polium a member of Lamiaceae family is a widely used plant in Algerian traditional medicine; however, there are few reports on its use as a healing agent. The aim of this study is to investigate the wound healing property of aerial part of this plant on excisional wounds.

Twenty adult male Wistar rats with an average weight of 180 g were used in this study. Post wound development, 10 rats received daily treatment with the plant ointment and the remaining rats served as control. Measurement of wound areas and calculation of closure percentages were made in order to evaluate wound healing macroscopically and a sample of the scar tissue formed was submitted at day 24 post treatment for a histological study.

Better and faster healing was observed in the Teucrium polium group compared to control. This improvement in wound healing was confirmed by the histological study which revealed that the effect of the plant lies in its stimulation of proliferative phase and its regulation of the inflammatory phase of wound healing. Based on these results, we could deduce that Teucrium polium enhance healing of excisional wounds.

Keywords

Excision, Phytotherapy, Rat, Teucrium polium, Wound healing