*Associate Professor & Head, Department of Oral Medicine & Radiology, Genesis Institute of Dental Sciences & Research,, Ferozepur (152201)
1Head Department of Oral Medicine & Radiology
2Department of Oral Medicine & Radiology, Genesis Institute of Dental Sciences & Research,, Ferozepur
3Department of Oral & Maxillofacial Surgery, Sri Guru Ram Das Dental College, Amritsar.
4Department of Oral Medicine & Radiology, Genesis Institute of Dental Sciences & Research, Ferozepur
Mandibulofacial dysostosis (Treacher Collin Syndrome) is an autosomal genetic disorder that probably derives from inhibition of the facial structures from the first & second branchial arches. The facial pattern of the syndrome is a convex facial profile with a prominent nose above the retruded chin. The eyes are deformed by antimongoloid slant of the palpebral fissures and facial bones are hypoplastic. The alterations are caused by mutation in gene 5q32-33.1, which encodes the nucleolar phosphoprotein treacle.
