1Post Graduate Student, Department of Conservative Dentistry and Endodontics, Sri Guru Ram Das Institute of Dental Sciences and Research, Amritsar, Punjab, India
2Professor and Head of Department, Department of Conservative Dentistry and Endodontics, Sri Guru Ram Das Institute of Dental Sciences and Research, Amritsar, Punjab, India
3Private Practitioner, Amritsar, Punjab, India
4Professor, Department of Conservative Dentistry and Endodontics, Sri Guru Ram Das Institute of Dental Sciences and Research, Amritsar, Punjab, India
*Corresponding Author: Dr. Harkiran Sahiwal, Post Graduate Student, Department of Conservative Dentistry and Endodontics, Sri Guru Ram Das Institute of Dental Sciences and Research, Amritsar, Punjab, India, Email: harkiransahiwal@gmail.com
Online Published on 23 July, 2024.
With the advent of adhesive restorations modern dentistry has been transformed into a minimally invasive and conservative modality no longer dependent on excess tooth structure removal for retention. Though it has many strengths adhesive dentistry presents with a new set of problems, the biggest of which is instability and degeneration of the adhesive dentin bond. This review article focuses on the reasons for the failure of resin-dentin adhesive bonds like release of matrix metalloproteinases (MMPs) and cysteine cathepsins and discusses various protocols (ethanol wet bonding) and materials (proanthocyanidins, cross-linkers, MMP-Inhibitors etc.) which can be used to increase the longevity of these bonds and ensure long-term stable restorations.
Resin-dentin bond, Biomodification, Matrix metalloproteinases (MMPs), Collagen-crosslinkers, MMP-inhibitors
