Peridens: review of etiopathogenesis and clinical presentations-Six case reports

Supernumerary teeth are infrequent developmental alterations manifesting either within or along the dental arches. They may involve any region; or may be associated with syndromic or non-syndromic conditions. All supplementary teeth are supernumerary teeth but not all supernumerary teeth can be supplementary teeth. A variety of supernumerary teeth that erupt ectopically either buccally or lingually to the normal arch is known as peridens.

This paper stresses upon review of etiopathogenesis of supernumerary teeth development such as heredity factors, genetics, environmental factors, numerous developmental disorders, mutations, phylogeny, and dichotomy theories of tooth germ differentiaion, dysregulation of Hedgehog FGF, Wnt, TNF and BMP families and growth morphogenetic proteins (BMPs and FGF family). This paper enlightens the budding young dynamic dental professionals about etiopathogenesis of developmental alterations of supernumerary.