Bulletin of Pure & Applied Sciences- Chemistry
  • Year: 2017
  • Volume: 36c
  • Issue: 1

A novel route for C-N coupling reaction: Alternative synthesis of 2-N-benzylaminoquinoline-3-carbonitrile in aqueous media

Department of Chemistry, Swami Vivekanand Subharti University, Meerut-250005, Uttar Pradesh, India

*Corresponding Author: Dr Shraddha Upadhyay, Department of Chemistry, Swami Vivekanand Subharti University, Meerut-250005, U.P, India. E-mail: dr.shrupa@gmail.com

Online published on 12 January, 2018.

Abstract

The present work relates to a process for C-N Coupling which can be used in a variety of chemical reactions. Work provides a process for C-N coupling between aryl halide and aliphatic amines also a low-cost process for C-N Coupling. It is to develop a process for C-N coupling that explores Buchwald-Hartwig amination reaction. Process may use for making N-alkylaminoquinoline which has industrial applications as a ligand.

Keywords

N-alkylaminoquinoline, Ligand, Buchwald-Hartwig amination reaction, CN Coupling