1Department of Chemistry, Mahatma Gandhi College, University of Kerala, Thiruvananthapuram.
*Corresponding Author Balachandran S, Department of Chemistry, Mahatma Gandhi College, University of Kerala, Thiruvananthapuram. E-mail: sbcnair@gmail.com
Online published on 28 February, 2018.
The yellow colored pigment, curcumin present in turmeric is responsible for its various biological activities like antioxidant, anti-inflammatory and anticarcinogenic activity. Different functional group present in curcumin includes a β-diketone group, carbon-carbon double bond and two phenyl rings with hydroxy and methoxy substituents. A controversy exists in literature on the site and mechanism for the antioxidant activity (AOA), the keto-enol/phenolic moiety present in curcumin. In the present work AOA of curcuminoids and its boron complex with oxalic acid-rubrocurcumin analogues were conducted which differ in the substituent in the benzene ring. Since in rubrocurcumin analogue β-diketone group is blocked through bonding with boron its influence will be absent in its antioxidant activity.
Curcumin, antioxidant, rubrocurcumin, β-diketone
